Everyone who needs an organ transplant deserves an optimal match
At Pirche, we revolutionize transplantation compatibility and immunological risk assessment with a fully digital and cutting-edge epitope matching technology to provide clinicians a data-driven decision support tool.
Our platform utilizes advanced algorithms to enhance donor-recipient matching accuracy, long-term immune risk, ultimately improving transplant outcomes worldwide.
Why choose Pirche?
Precision
Epitope-level matching provides a finer degree of compatibility assessment over traditional HLA matching.
Reliability
Backed by extensive research in over 250,000 cases and >80 publications on clinical validation, PIRCHE has been validated across all solid-organ types and bone marrow transplantation.
Innovation
Our dedication to continual refinement of algorithms ensures our technology stays at the forefront of transplantation science and the clinician and the transplant patient receive world-class HLA risk assessments
Our Partners
DIGITAL PRODUCT STREAMS
Transplant Medicine
Compatibility between a recipient and a donor is at the core of for the success in solid-organ and bone marrow transplantation.
PIRCHE focuses on predicting how well the recipient's immune system will recognize and respond to the donor organ based on HLA epitopes.
High complexity testing for HLA genes are utilized for matching, and understanding immune risk for each pair. This can improve the likelihood of a successful transplant by:
Minimizing immune rejection
Guiding immunosuppressive therapy.
Optimizing biomarker monitoring
Donor selection
DIGITAL PRODUCT STREAMS
Cell Therapy
PIRCHE epitope matching reduces the risk of immune rejection, by identifying donors whose cells are less likely to be recognised as foreign.
This is crucial in allogeneic cell therapy where mismatched donor cells can lead to immune-mediated destruction of the therapeutic cells.
PIRCHE can help:
Identify optimal ‘off-the-shelf’ therapy
Minimize Graft versus Host Disease
Optimize therapy efficacy and safety
TECHNOLOGY
Proprietary platform
The Pirche TxPredictor platform uses T and B cell epitope predictors, allowing clinicians and laboratories to interact with their patient’s compatibility data like never before
Highlights and Benefits
Custom analysis modules
Proprietary applications
T-cell
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B-cell
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Contact us
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