PUBLISHED BY
Ladowski, J.M.; Mullins, Haddon; Romine, Margaret; Kloda, David; Young, Carlton; Hauptfeld-Dolejsek, Vera; Houp, Julie; Locke, Jayme
PUBLISHED IN
Human Immunology
PATIENTS
113
ABSTRACT
HIGHLIGHTS
- Retrospective application of high-resolution incompatibility scoring to gauge the performance of EMMA, HLAMatchmaker and PIRCHE-II in predicting dn DSA formation in simultaneous pancreas-kidney (SPK) recipients.
- Statistically significant factors associated with dn DSA development are found for PIRCHE II and HLA Matchmaker.
- The report demonstrates that an increased incompatibility score predicts dn DSA development and worse renal and pancreas graft outcomes with dnDSA development.